Explain how calcium channel blockers reduce blood pressure and name a commonly used dihydropyridine calcium channel blocker in India.
Answer
They inhibit L‑type calcium channels in vascular smooth muscle, causing vasodilation and lower BP; example: amlodipine.
The correct answer is They inhibit L‑type calcium channels in vascular smooth muscle, causing vasodilation and lower BP; example: amlodipine. — Give a common Indian dihydropyridine blocker – amlodipine.
Step-by-step solution
- Identify that calcium channel blockers act on smooth muscle to reduce contractility.
- Explain inhibition of L‑type calcium channels limits Ca²⁺ influx into smooth muscle cells.
- State that reduced Ca²⁺ causes vasodilation, lowering systemic vascular resistance and BP.
- Give a common Indian dihydropyridine blocker – amlodipine.
Common mistake: Confusing calcium channel blockers with beta‑blockers for BP control
Concept tested: Calcium channel blocker action in hypertension
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