Explain why a live attenuated measles vaccine elicits stronger immunity than an inactivated vaccine.
Answer
Live attenuated vaccine replicates in host, inducing robust cellular and humoral responses, whereas inactivated vaccine cannot replicate.
Step-by-step solution
- Define live attenuated and inactivated vaccines
- Explain that live vaccine replicates and presents antigens over time
- Describe the resulting strong T‑cell and antibody responses
- Contrast with the limited immune response to inactivated vaccine
Common mistake: Assuming inactivated vaccines produce stronger antibody titres
Concept tested: Vaccine immunology
Published · How this solution was prepared and checked
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